• Currency:
0

Thymosin Alpha 1 10mg

£44.00
  • Ex Tax:£36.67
  • Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. [1]

    It was the first of the peptides from Thymosin Fraction 5 to be completely sequenced and synthesized. Unlike β thymosins, to which it is genetically and chemically unrelated, thymosin α1 is produced as a 28-amino acid fragment, from a longer, 113-amino acid precursor, prothymosin α.[2]

    Thymosin α1 is believed to be a major component of Thymosin Fraction 5 responsible for the activity of that preparation in restoring immune function in animals lacking thymus glands. It has been found to enhance cell-mediated immunity in humans as well as experimental animals.[3]


    Usage: 

    Product is prepared for LABORATORY RESEARCH USE ONLY. The product may not be used for other purposes.

    References:

    1.  Manrow RE, Leone A, Krug MS, Eschenfeldt WH, Berger SL (Jul 1992). "The human prothymosin alpha gene family contains several processed pseudogenes lacking deleterious lesions"Genomics13 (2): 319–31. doi:10.1016/0888-7543(92)90248-QPMID 1612591.
    2. ^ Garaci E (September 2007). "Thymosin alpha1: a historical overview". Ann. N. Y. Acad. Sci1112: 14–20. doi:10.1196/annals.1415.039PMID 17567941.
    3. ^ Wara DW, Goldstein AL, Doyle NE, Ammann AJ (January 1975). "Thymosin activity in patients with cellular immunodeficiency". N. Engl. J. Med292 (2): 70–4. doi:10.1056/NEJM197501092920204PMID 1078552.


    Source: Wikipedia

    Wikipedia text is published under the Creative Commons Attribution Share-Alike licence (CC-BY-SA) and is re-distributed here under that licence. Licensing information can be found at http://creativecommons.org/licenses/by-sa/3.0


    Write a review

    Please login or register to review